The pharmaceutical industry is an important industry related to people's physical and mental health, including pharmaceuticals, medical machinery, sanitary materials and other fields, and occupies an important position in the national economy. Titanium alloy materials are widely used in the pharmaceutical industry because they are non-toxic and harmless, and have good compatibility with the human body. ASTM F136 Titanium Medical Wire Gr7 Ti-0.2Pd Titanium Wire Gr2 Pure Titanium Foil Gr23 Ti-6Al-4V ELI Titanium Tube
In pharmaceutical production, because the production of medicines is inseparable from acids, alkalis and salts, pharmaceutical equipment is easily damaged by corrosion. The use of steel equipment not only cannot solve the problem of serious equipment corrosion, but also causes a lot of loss of human, material and financial resources, affecting normal production. The use of titanium equipment solves this problem very well.
In the production of several main commonly used drugs, the equipment made of titanium has good corrosion resistance and obtains considerable economic benefits.
1. Production of vitamin B1
In my country, the hydrogen chloride conversion method is often used to produce vitamin B1, and the finished product is dried by cyclone and separated by two cyclones. The medium is thiamine hydrochloride, the pH value is 2.5, and the temperature is 110 °C, which is highly corrosive. The original drying device was made of stainless steel, and the inner wall was corroded and perforated after more than a year of use, and seriously polluted the medicine.
After adopting titanium screw feeder, cyclone separator, vortex body, hopper and discharge pipe and titanium lining of exhaust box, the production qualification rate of vitamin B1 has been increased from the highest 95% to 100%, and the equipment has not been corroded for more than 7 years , the cost of titanium can be recovered in 3 months.
2. Vitamin C production
Vitamin C is sorbitol as raw material, fermented into sorbose with black vinegar bacteria, and then fermented with Pseudomonas to obtain low-concentration gulonic acid, which is converted into finished product by hydrogen chloride after concentration.
Titanium is very resistant to corrosion in high temperature coronic acid. In the production process of this product, a titanium tubular heat exchanger, a titanium DHC-500 disc sinking type automatic slag discharge centrifuge, and a TC4 cast impeller are used, and no corrosion has been found for many years.
3. Antibiotic production
The main raw material for the chemical synthesis of chloramphenicol (an antibiotic) is methyl dichloroacetate, which contains about 2% chlorinated alkene and trichloroethylene. If steel equipment is used in the refining process, it is prone to severe corrosion, and titanium is used instead. The equipment has been intact since its manufacture.
No comments:
Post a Comment